Recently Uploaded (last two weeks)
- Chinese genealogy = 家譜
- This genealogy in my possession may serve as a sample of Chinese genealogical records the originals of which may be rare today.
- Chor, Louis
- Transverse Relaxometry with Stimulated Echo Compensation
- Presented is a fitting model for transverse relaxometry data
acquired with the multiple-refocused spin-echo sequence.
The proposed model, requiring no additional data input or
pulse sequence modifications, compensates for imperfections
in the transmit field and radiofrequency (RF) profiles.
Exploiting oscillatory echo behavior to estimate alternate coherence
pathways, the model compensates for prolonged
signal decay from stimulated echo pathways yielding precise
monoexponential T2 quantification. Verified numerically and
experimentally at 4.7 T in phantoms and the human brain,
over 95% accuracy is readily attainable in realistic imaging
situations without sacrificing multislice capabilities or requiring
composite or adiabatic RF pulses. The proposed model
allows T2 quantitation in heterogeneous transmit fields and
permits thin refocusing widths for efficient multislice
imaging. Magn Reson Med 64:1005–1014, 2010. VC 2010
- Marc Lebel
- Evolution of RLSB, a nuclear-encoded S1 domain RNA binding protein associated with post-transcriptional regulation of plastid-encoded rbc L mRNA in vascular plants
- Background: RLSB, an S-1 domain RNA binding protein of Arabidopsis, selectively binds rbcL mRNA and co-localizes
with Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) within chloroplasts of C3 and C4 plants. Previous
studies using both Arabidopsis (C3) and maize (C4) suggest RLSB homologs are post-transcriptional regulators
of plastid-encoded rbcL mRNA. While RLSB accumulates in all Arabidopsis leaf chlorenchyma cells, in C4 leaves
RLSB-like proteins accumulate only within Rubisco-containing bundle sheath chloroplasts of Kranz-type species, and
only within central compartment chloroplasts in the single cell C4 plant Bienertia. Our recent evidence implicates
this mRNA binding protein as a primary determinant of rbcL expression, cellular localization/compartmentalization,
and photosynthetic function in all multicellular green plants. This study addresses the hypothesis that RLSB is a
highly conserved Rubisco regulatory factor that occurs in the chloroplasts all higher plants.
Results: Phylogenetic analysis has identified RLSB orthologs and paralogs in all major plant groups, from ancient
liverworts to recent angiosperms. RLSB homologs were also identified in algae of the division Charophyta, a lineage
closely related to land plants. RLSB-like sequences were not identified in any other algae, suggesting that it may
be specific to the evolutionary line leading to land plants. The RLSB family occurs in single copy across most
angiosperms, although a few species with two copies were identified, seemingly randomly distributed throughout
the various taxa, although perhaps correlating in some cases with known ancient whole genome duplications.
Monocots of the order Poales (Poaceae and Cyperaceae) were found to contain two copies, designated here
as RLSB-a and RLSB-b, with only RLSB-a implicated in the regulation of rbcL across the maize developmental
gradient. Analysis of microsynteny in angiosperms revealed high levels of conservation across eudicot species
and for both paralogs in grasses, highlighting the possible importance of maintaining this gene and its surrounding
Conclusions: Findings presented here indicate that the RLSB family originated as a unique gene in land plant evolution,
perhaps in the common ancestor of charophytes and higher plants. Purifying selection has maintained this as a highly
conserved single- or two-copy gene across most extant species, with several conserved gene duplications. Together
with previous findings, this study suggests that RLSB has been sustained as an important regulatory protein throughout
the course of land plant evolution. While only RLSB-a has been directly implicated in rbcL regulation in maize, RLSB-b
could have an overlapping function in the co-regulation of rbcL, or may have diverged as a regulator of one or more
other plastid-encoded mRNAs. This analysis confirms that RLSB is an important and unique photosynthetic regulatory
protein that has been continuously expressed in land plants as they emerged and diversified from their ancient
- Yerramsetty, Pradeep
- Unsettling Our Practice: Decolonizing Description at the University of Alberta Libraries
- This poster provides an overview of the work of the University of Alberta Libraries to critically examine and revise its descriptive metadata practices to more accurately, appropriately, and respectfully represent Indigenous peoples and contexts. The poster was presented at the Diversity by Design Symposium in Toronto, Ontario, Canada, 14 September 2017.
- Farnel, Sharon
- Truth Machine: The Political Economy of Command and Control
- This article looks at the socio-economic context of Gilles Deleuze's "Postscript on the Societies of Control", and interrogates the technological underpinning of the shift from discipline to control in the centres of advanced capitalism. The paper argues that developments in computer science and cybernetics in the first half of the twentieth century led to a cybernetic capitalism in which statistics, probability, and binary logic create a "post-truth" which serves to structure the self-control and self-regulation of docile subjects. In the end, it argues for a reclamation of "democratic excess" as a means to regain agency and the full richness of the human experience of truth.
- Sam Popowich